Foundayo is Eli Lilly's brand of orforglipron, a once-daily GLP-1 pill the FDA approved on April 1, 2026 for chronic weight management in adults with obesity, or overweight with a weight-related condition [3].
- LillyDirect price
- $149 (0.8 mg), $149 (2.5 mg), $199 (5.5 mg), $299 (9, 14.5, 17.2 mg) a month [1]
- Temporary cut ends
- Dec 31, 2026, for the 2.5 mg and 5.5 mg prices [1]
- Refill rule
- 14.5 mg and 17.2 mg stay at $299 only if refilled within 45 days [1]
- With covered insurance
- As little as $25 a month [4]
- Checked
- Oct 17, 2026
Foundayo price by dose
LillyDirect counts a Foundayo month as 30 days [1]. The low prices on the second and third doses are a promotion with an end date, and the two highest doses carry a refill-timing condition like Zepbound's. For all GLP-1 prices in one place, see the GLP-1 Price Tracker.
| Dose or channel | Price a month | Terms | Checked | Source |
|---|---|---|---|---|
| LillyDirect, 0.8 mg (starting dose) | $149 | Drug only. Prescription needed. | Oct 17, 2026 | Lilly [1] |
| LillyDirect, 2.5 mg | $149 | Temporary price through Dec 31, 2026. Ro lists the regular price as $199. | Oct 17, 2026 | Lilly [1]; Ro [6] |
| LillyDirect, 5.5 mg | $199 | Temporary price through Dec 31, 2026. Ro lists the regular price as $299. | Oct 17, 2026 | Lilly [1]; Ro [6] |
| LillyDirect, 9 mg | $299 | Drug only | Oct 17, 2026 | Lilly [1] |
| LillyDirect, 14.5 mg or 17.2 mg | $299 | Only if refilled within 45 days (Self-Pay Journey Program). Drugs.com reported $349 when not refilled in time. | Oct 17, 2026 | Lilly [1]; Drugs.com [7] |
| Commercial plan covers Foundayo, with savings card | As little as $25 | Government plans excluded. Caps not published in the sources we read. | Oct 17, 2026 | Lilly [4] |
| Medicare GLP-1 Bridge | $50 | One-month supply, if you meet the criteria | Oct 17, 2026 | CMS [5] |
| Ro (telehealth) | $149 to $299 plus membership | Promo prices need sign-up by Dec 31, 2026. Membership $39 first month, then $74 to $149. | Oct 17, 2026 | Ro [6] |
| TrumpRx | Not listed | Foundayo was not among the GLP-1s on the TrumpRx home page | Oct 17, 2026 | TrumpRx [8] |
What it will really cost over a year
- Step-ups. The label starts at 0.8 mg, then 2.5 mg after at least 30 days, then 5.5 mg after at least 30 more days. After that the prescriber may move to 9, 14.5 or 17.2 mg, with at least 30 days on each [2].
- The promotion ending. Starting in 2027, the 2.5 mg and 5.5 mg months may cost $199 and $299, the regular prices Ro lists [6], unless Lilly extends the cut.
- Late refills on the top doses. Refill 14.5 mg or 17.2 mg after 45 days and you lose the $299 price [1].
- The prescriber. LillyDirect needs a prescription; telehealth programs add a membership, such as Ro's [6].
Does Foundayo work?
The label reports two 72-week trials. In adults without diabetes, average weight loss was 7.4% on 5.5 mg, 8.3% on 9 mg and 11.1% on 17.2 mg, against 2.1% on placebo. In adults with type 2 diabetes, it was 5.1%, 7.0% and 9.6%, against 2.5% [2]. These are averages; individual results vary.
Foundayo is not tirzepatide. Zepbound (tirzepatide) is a weekly injection; in SURMOUNT-1 its 15 mg dose produced 20.9% average weight loss at 72 weeks [9]. The trials differ, so the numbers are not a head-to-head test. For the two pills side by side, see Foundayo vs Wegovy pill; the Wegovy pill costs $149 to $299 a month [10].
How to take Foundayo
- Once a day, with or without food. Swallow the tablet whole; do not break, crush or chew it. No more than one tablet a day [2].
- Lilly's approval release says it can be taken at any time of day [3].
- Missed dose: take it as soon as possible and do not double the next one. If you miss 7 or more days in a row, the label says to restart at a lower dose [2].
- Some drugs change the dose: with strong CYP3A4 inhibitors, the label caps Foundayo at 9 mg a day [2]. Tell your prescriber about every medicine you take.
- Store at room temperature, 68 to 77 F [11].
Side effects
| Side effect | Placebo | 5.5 mg | 9 mg | 17.2 mg |
|---|---|---|---|---|
| Nausea | 10% | 26% | 34% | 35% |
| Constipation | 9% | 20% | 27% | 24% |
| Diarrhea | 11% | 21% | 23% | 25% |
| Vomiting | 4% | 13% | 21% | 24% |
Safety warnings on the Foundayo label
Foundayo has a boxed warning: other GLP-1 drugs caused thyroid C-cell tumors in rodents. Orforglipron did not, because it is not active in rodents, so the human risk is undetermined. Do not use it with a personal or family history of medullary thyroid carcinoma or MEN 2 [2]. Stomach pain that is severe and does not stop can signal pancreatitis, and swelling, rash or trouble breathing can signal an allergic reaction; both need prompt care. If you use birth control pills, the label says to switch to a non-oral method or add a barrier method for 30 days after starting and after each dose increase. It may harm a fetus, so stop when pregnancy is recognized; breastfeeding is not recommended [2]. For an emergency, call 911.
How to get Foundayo
- Get a prescription from your clinician or a telehealth program. Foundayo is prescription-only [1].
- Fill it through LillyDirect, which began shipping April 6, 2026 with free home delivery or free retail pickup, or at a retail pharmacy; retail shipping began April 9, 2026 [4].
- With commercial insurance, ask whether your plan covers it and use Lilly's savings card [4]. Our guide to how plans decide on Lilly's weight drugs lists the steps.
- On Medicare Part D, check the GLP-1 Bridge criteria on our Medicare page.
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Telehealth programs that sell Foundayo (clean or caution only)
- Clean
- Price
- $149 to $299 plus membership [6]
- What you get
- Foundayo at every strength, plus the Wegovy pill and pens and Zepbound
- FDA record
- No FDA warning letter found as of Oct 17, 2026
- BBB
- Not yet checked
- Note
- Promo prices need sign-up by Dec 31, 2026
- Clean
- Price
- Brand plan $99 to $149 a month, drug billed separately [12]
- What you get
- Prescribes brand GLP-1s including Foundayo
- FDA record
- No FDA warning letter found as of Oct 17, 2026
- BBB
- Not yet checked
- Note
- Labs not included
Other options: Wegovy pill cost, Zepbound cost and online GLP-1 programs compared.
Questions people ask
How much does Foundayo cost without insurance?
On LillyDirect, Foundayo costs $149 a month for 0.8 mg and 2.5 mg, $199 for 5.5 mg and $299 for 9, 14.5 and 17.2 mg (checked Oct 17, 2026). The 2.5 mg and 5.5 mg prices are a temporary cut through Dec 31, 2026 [1].
What is Foundayo?
Foundayo is orforglipron, a once-daily GLP-1 pill from Eli Lilly. The FDA approved it on April 1, 2026 for adults with obesity, or overweight with a weight-related condition, alongside diet and exercise [3].
Is Foundayo a GLP-1, and is it the same as tirzepatide?
How effective is Foundayo for weight loss?
In the label's 72-week trial of adults without diabetes, people lost an average of 7.4% on 5.5 mg, 8.3% on 9 mg and 11.1% on 17.2 mg, against 2.1% on placebo [2].
How do I take Foundayo?
Does Medicare cover Foundayo?
Is Foundayo covered by insurance?
Is Foundayo safe?
It is FDA-approved, with label warnings. The most common side effects were nausea, constipation, diarrhea and vomiting, and 8% stopped for side effects against 3% on placebo. It has a boxed thyroid tumor warning and should not be used with a personal or family history of medullary thyroid carcinoma or MEN 2 [2].
Sources
12 cited
- Foundayo on LillyDirect: self-pay prices. Eli Lilly and Company (LillyDirect), Oct 17, 2026.
- Foundayo (orforglipron) prescribing information. Eli Lilly and Company (FDA-approved labeling), Jul 2026.
- FDA approves Lilly's Foundayo (orforglipron). Eli Lilly and Company, Apr 1, 2026.
- Foundayo now available: Lilly's oral GLP-1 pill for weight loss. Eli Lilly and Company, Apr 9, 2026.
- Medicare GLP-1 Bridge: information for pharmacies. Centers for Medicare & Medicaid Services, Oct 17, 2026.
- Ro weight loss pricing. Ro, Oct 17, 2026.
- How much does Foundayo cost?. Drugs.com, Jul 22, 2026.
- TrumpRx.gov home page. TrumpRx.gov (US government), Oct 17, 2026.
- Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). New England Journal of Medicine (PubMed), Jun 4, 2022.
- Wegovy self-pay offer. Novo Nordisk (NovoCare Pharmacy), Oct 17, 2026.
- Foundayo NDA 220934 approval package. US Food and Drug Administration, Apr 1, 2026.
- Found offer terms. Found, Oct 17, 2026.
This page is general information, not medical advice. Talk with a licensed clinician about your own care.